The Vatican said on Wednesday that Francis had a quiet night at Rome's Gemelli hospital.
If the past few days are any guide, the 88-year-old Argentine will likely follow the Vatican's spiritual retreat remotely while his physical and respiratory therapy continues.
The Pope's weekly Wednesday general audience was cancelled anyway since the entire Vatican hierarchy is on retreat this week as part of the Lenten spiritual exercises that have been a mainstay of the Jesuit Pope's pontificate.
Doctors have said Francis is making slow, gradual improvements and this week declared that he is no longer in imminent danger of death as a result of the complex respiratory infection he had when he was admitted on February 14.
But they remain cautious, given the complexity of his condition and overall fragility, and say he needs to remain hospitalised for an unspecified number of days.
Another medical update is expected later on Wednesday.
Thursday marks the 12th anniversary of Francis' election as the 266th pope.
The former Cardinal Jorge Mario Bergoglio was elected on the fifth ballot of the 2013 conclave that was called after Pope Benedict XVI resigned.
While Francis has praised Benedict's humility in stepping down and said that he might follow in his footsteps, more recently he has said the papacy is a job for life.
The Holy See has not said how the anniversary, which is a public holiday in the Vatican, might be commemorated.
Another milestone comes on Friday, when Francis marks four weeks or 28 days of hospitalisation.
St John Paul II has the record for a hospital stay, at 55 days in 1981 when he underwent a minor surgical operation and was then treated for a cytomegalovirus infection.
Francis is on track to equal the second-longest stay, 28 days, which John Paul recorded in 1994 when he had surgery to repair his right hip joint after he fractured his right femur in a fall, according to Gemelli hospital.
The Pope recorded an audio message last week to thank people for their prayers, though the weakness and breathlessness of his voice made clear just how frail he was.
