This fight took place in Maude St, near Fryers St, at around 1am on March 2.
A 23-year-old Shepparton man was allegedly slashed around his neck and upper body with a broken glass bottle and was taken to GV Health via ambulance, police said.
A 52-year-old Shepparton man also allegedly sustained lacerations and was knocked unconscious during the fight.
After reviewing CCTV footage, police believe six people were involved in the brawl; however, multiple intoxicated members of the public allegedly entered the established crime scene and assaulted officers, which resulted in four people being sprayed with capsicum spray, police said.
Six people involved in the fight have been arrested between Monday and Wednesday, with all charged with affray.
They include a 27-year-old Mooroopna man, a 31-year-old Mooroopna woman, a 33-year-old Shepparton man, and a 34-year-old Mooroopna man, as well as the 23-year-old Shepparton man and 52-year-old Shepparotn man who were injured in the incident.
The 33-year-old Shepparton man has also been charged with conduct endangering serious injury.
All six have been bailed to appear in Shepparton Magistrates’ Court in July.
Police investigations into the people who entered the crime scene are ongoing.